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Nagappa, A. N.
- Wound Healing Activity of the Leaves of Thespesia populnea
Authors
Source
Journal of Natural Remedies, Vol 7, No 1 (2007), Pagination: 120-124Abstract
Objective: To screen the wound healing activity of petroleum ether, alcohol and aqueous extracts of leaves of Thespesia populnea on excision and incision wound models in albino rats. Materials and methods: The different extracts of the leaves of Thespesia populnea are obtained by successive soxhlet extraction with petroleum ether, alcohol and aqueous were subjected to acute toxicity studies. The extracts were screened for wound healing properties in the excision and incision wound models in albino rats of either sex under light ether anesthesia. Result: All the three extracts showed significant increase in wound contraction and formation of scar in excision wound model. These extracts showed significant increase in the breaking strength of resutured incision wound as compared to control group (P<0.001). Glycosides, flavonoids, alkaloids, and phytosterols have been reported to be present in leaves of T. populnea. Conclusion: The results of the present study indicate that aqueous extract of T. populnea leaves has more significant wound healing property than the petroleum ether and alcoholic extracts in excision and incision wound models. The presence of flavonoids, alkaloids and phytosterols in the leaves of the plant may be responsible for wound healing activity.Keywords
Thespesia populnea, Incision and Excision Wound ModelsFull Text
- Drug Receptor Interaction Vis-a-Vis Alternative View of Enzyme Reactions Proposed by Dewar and Storch
Authors
1 Birla Institute of Technology and Science, Pilani - 333 031, Rajasthan, IN
Source
Journal of Surface Science and Technology, Vol 18, No 3-4 (2002), Pagination: 191-194Abstract
An alternative view of drug receptor interaction, which is inspired by the alternative view of enzyme reaction of Dewar and Storch is proposed. It has been suggested that dehydration of receptor site should precede the interaction of drug with receptor. The dehydration step has hitherto not been considered in literature.Keywords
Drug, Receptor, Enzyme.
- Transport Across Liquid Membrane Containing Vitamin D3, (Cholecalciferol)
Authors
1 Birla Institute of Technology and Science, Pilani - 333 031, Rajasthan, IN
2 SCS College of Pharmacy, Harapanahalli - 583 131, IN
Source
Journal of Surface Science and Technology, Vol 18, No 1-2 (2002), Pagination: 43-49Abstract
Transport through liquid membranes generated by vitamin D3 in series with a supporting membrane, has been studied. The data have been obtained to show the formation of liquid membrane in series with the supporting membrane. Transports of cations, glucose, and phosphate have been studied in prssence of Vitamin D3. The data on the modification in the permeability of cations, glucose and phosphate has been shown to be consistent with the reported biological actions of vitamin D3.Keywords
Vitamin D3, Cholecalciferol, Liquid Membrane and Surface Activity.- Evaluation of the Quality and Contents of Obesity Patient Education on Internet
Authors
1 Department of Pharmaceutical Management, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, IN
Source
Journal of Pharmaceutical Research, Vol 11, No 1 (2012), Pagination: 15-19Abstract
Objective: To evaluate web-based obesity patient education material for HSWG criteria and core education concepts.Design: Evaluation of the web sites which contain information relating to obesity.
Setting: Listing of web-sites was obtained from 14 search engines with the help of Copernic agent professional version 6.21. The search for websites was undertaken using the keyword "obesity".
Participants: Out of 162 web-sites retrieved from meta search engine, 54 sites themselves provide patient information and so considered for evaluation.
Intervention(s): Data obtained was analyzed by cluster analysis and classified into four categories with respect to quality.
Main Outcome Measure(s): Twelve core educational concepts specific for obesity patient education were developed and the websites were evaluated for compliance. The quality of all the websites providing patient information for obesity were evaluated based on the extent of their adherence to Health Summit Working Group (HSWG) criteria. On the basis of the sum of scores obtained from "obesity core educational concepts" and HSWG criteria, websites were graded as excellent, medium, good and average.
Results: Considerable variability in quality of patient education web-sites was found with respect to core educational concepts and HSWG criteria. Spearman correlation analysis showed significant correlation (P=0.016) at 0.05 level, between total scores of core educational concept and HSWG criteria.
Conclusions: Inclusion of stress management, role of family support, enhancement in customized content like chat rooms, discussion forums, customized alerts and easier feedback mechanisms will be a significant development in the direction of patient centred obesity care.
Keywords
Obesity, Hon Code, HSWG, Patient Education.Full Text